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Straight facts about Hepatits from the Center for Disease Control
HEPATITIS C FACT SHEET
by Centers for Disease Control and Prevention
Hepatitis C Fact SheetAugust 27, 2002
| SIGNS & SYMPTOMS |
80% of persons have no signs or symptoms. |
- jaundice
- fatigue
- dark urine
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- abdominal pain
- loss of appetite
- nausea
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| CAUSE |
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| LONG-TERM EFFECTS |
- Chronic infection: 75-85% of infected persons
- Chronic liver disease: 70% of chronically infected persons
- Deaths from chronic liver disease: <3%
- Leading indication for liver transplant
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| TRANSMISSION |
- Occurs when blood or body fluids from an infected person enters the body of a person who is not infected.
- HCV is spread through sharing needles or "works" when "shooting" drugs, through needlesticks or sharps exposures on the job, or from an infected mother to her baby during birth.
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| RECOMMENDATIONS FOR TESTING BASED ON RISK FOR HCV INFECTION |
Persons at risk for HCV infection might also be at risk for infection with hepatitis B virus (HBV) or HIV.
| Recommendations for Testing Based on Risk for HCV Infection |
| Persons |
Risk of Infection |
Testing Recommended? |
| Injecting drug users |
High |
Yes |
| Recipients of clotting factors made before 1987 |
High |
Yes |
| Hemodialysis patients |
Intermediate |
Yes |
| Recipients of blood and/or solid organs before 1992 |
Intermediate |
Yes |
| People with undiagnosed liver problems |
Intermediate |
Yes |
| Infants born to infected mothers |
Intermediate |
After 12-18 mos. old |
| Healthcare/public safety workers |
Low |
Only after known exposure** |
| People having sex with multiple partners |
Low |
No* |
| People having sex with an infected steady partner |
Low |
No* |
* Anyone who wants to get tested should ask their doctor.
** View current post-exposure prophylaxis recommendations (PDF). |
| PREVENTION |
- There is no vaccine to prevent hepatitis C.
- Do not shoot drugs; if you shoot drugs, stop and get into a treatment program; if you can't stop, never share needles, syringes, water, or "works", and get vaccinated against hepatitis A & B.
- Do not share personal care items that might have blood on them (razors, toothbrushes).
- If you are a health care or public safety worker, always follow routine barrier precautions and safely handle needles and other sharps; get vaccinated against hepatitis B. (View current post-exposure prophylaxis recommendations [PDF].)
- Consider the risks if you are thinking about getting a tattoo or body piercing. You might get infected if the tools have someone else's blood on them or if the artist or piercer does not follow good health practices.
- HCV can be spread by sex, but this is rare. If you are having sex with more than one steady sex partner, use latex condoms*** correctly and every time to prevent the spread of sexually transmitted diseases. You should also get vaccinated against hepatitis B.
- If you are HCV positive, do not donate blood, organs, or tissue.
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TREATMENT & MEDICAL MANAGEMENT
National Institutes of Health fact sheet on treatment |
- HCV positive persons should be evaluated by their doctor for liver disease.
- Interferon and ribavirin are two drugs licensed for the treatment of persons with chronic hepatitis C.
- Interferon can be taken alone or in combination with ribavirin. Combination therapy is currently the treatment of choice.
- Combination therapy, using pegylated interferon and ribavirin, can get rid of the virus in up to 40% of those with genotype 1 and up to 80% for those with genotype 2 or 3.
- Drinking alcohol can make your liver disease worse.
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| STATISTICS & TRENDS
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- Number of new infections per year has declined from an average of 240,000 in the 1980s to about 25,000 in 2001.
- Most infections are due to illegal injection drug use.
- Transfusion-associated cases occurred prior to blood donor screening; now occurs in less than one per million transfused unit of blood.
- Estimated 3.9 million (1.8%) Americans have been infected with HCV, of whom 2.7 million are chronically infected.
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*** The efficacy of latex condoms in preventing infection with HCV is unknown, but their proper use may reduce transmission.
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